BCL2L1 抗体 (AA 89-151)
Quick Overview for BCL2L1 抗体 (AA 89-151) (ABIN1886696)
抗原
See all BCL2L1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 89-151
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纯化方法
- Purified by antigen-affinity chromatography.
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免疫原
- Synthetic peptide contain a sequence corresponding to a region within amino acids 89 and 151 of Human BCL2L1
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应用备注
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Suggested dilutions:
Western blotting: 1.500-1.3000
Immunohistochemistry: 1.100-1.250
Immunofluorescence: 1.100-1.200 -
限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- 0.1 M Tris-buffered saline with 10 % Glycerol (pH 7.0).0.01 % Thimerosal was added as a preservative.
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储存液
- Thimerosal (Merthiolate)
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注意事项
- Biohazard Informations: This product contains thimerosal which is hazardous.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.
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- BCL2L1 (BCL2-Like 1 (BCL2L1))
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别名
- BCL2L1
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背景
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The protein encoded by this gene belongs to the BCL-2 protein family.BCL-2 family members form hetero- or homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities.The proteins encoded by this gene are located at the outer mitochondrial membrane, and have been shown to regulate outer mitochondrial membrane channel (VDAC) opening.VDAC regulates mitochondrial membrane potential, and thus controls the production of reactive oxygen species and release of cytochrome C by mitochondria, both of which are the potent inducers of cell apoptosis.Two alternatively spliced transcript variants, which encode distinct isoforms, have been reported.The longer isoform acts as an apoptotic inhibitor and the shorter form acts as an apoptotic activator.[provided by RefSeq]
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分子量
- 19 kDa
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基因ID
- 598
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NCBI登录号
- NP_001182, NM_001191
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途径
- Apoptosis, Negative Regulation of intrinsic apoptotic Signaling
抗原
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