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BCL2L1 抗体 (AA 89-151)

This anti-BCL2L1 antibody is a 兔 多克隆 antibody detecting BCL2L1 in WB, IHC 和 IF. Suitable for 人.
产品编号 ABIN1886696
发货至: 中国

Quick Overview for BCL2L1 抗体 (AA 89-151) (ABIN1886696)

抗原

See all BCL2L1 抗体
BCL2L1 (BCL2-Like 1 (BCL2L1))

适用

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宿主

  • 148
  • 89
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克隆类型

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多克隆

标记

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This BCL2L1 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
  • 抗原表位

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    AA 89-151

    纯化方法

    Purified by antigen-affinity chromatography.

    免疫原

    Synthetic peptide contain a sequence corresponding to a region within amino acids 89 and 151 of Human BCL2L1
  • 应用备注

    Suggested dilutions:
    Western blotting: 1.500-1.3000
    Immunohistochemistry: 1.100-1.250
    Immunofluorescence: 1.100-1.200

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    0.1 M Tris-buffered saline with 10 % Glycerol (pH 7.0).0.01 % Thimerosal was added as a preservative.

    储存液

    Thimerosal (Merthiolate)

    注意事项

    Biohazard Informations: This product contains thimerosal which is hazardous.

    储存条件

    4 °C/-20 °C

    储存方法

    Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.
  • 抗原

    BCL2L1 (BCL2-Like 1 (BCL2L1))

    别名

    BCL2L1

    背景

    The protein encoded by this gene belongs to the BCL-2 protein family.BCL-2 family members form hetero- or homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities.The proteins encoded by this gene are located at the outer mitochondrial membrane, and have been shown to regulate outer mitochondrial membrane channel (VDAC) opening.VDAC regulates mitochondrial membrane potential, and thus controls the production of reactive oxygen species and release of cytochrome C by mitochondria, both of which are the potent inducers of cell apoptosis.Two alternatively spliced transcript variants, which encode distinct isoforms, have been reported.The longer isoform acts as an apoptotic inhibitor and the shorter form acts as an apoptotic activator.[provided by RefSeq]

    分子量

    19 kDa

    基因ID

    598

    NCBI登录号

    NP_001182, NM_001191

    途径

    Apoptosis, Negative Regulation of intrinsic apoptotic Signaling
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